What you are about to read is a quick representation of Eureka Lab Division and what it did to succeed in researching, developing and producing
the World ‘s Largest Range of Diagnostic Kits
for chromatographic analytical instruments
Many years ago, Dr. Gilberto Coppa and Dr. Stefano Sartori decided to pursue a professional path that few companies had dealt with:
the analytical procedures existing in clinical laboratories, thanks to the realization of
using HPLC, GC, GC-MS, LC-MS / MS chromatographic techniques.
From the very outset, they concentrated their activity on the development of an Analytical Method for the Determination of Urinary and Plasma Catecholamines in HPLC with Fluorimetric Revelation.
The decision to work with Catecholamine was due to the shared thought, along with many Oncologists, that the need of Formulating a Correct Diagnosis of cancer patients was fundamental and extremely important
The concentration of catecholamines (Noradrenaline, Adrenaline, Dopamine), which are a group of hormones produced by the adrenal gland, are greatly increased in biological fluids in the presence of such pathologies.
To help doctors to properly diagnose these tumor forms, they asked some laboratories about their problems and issues in their structures since the 1970s.
Here are some of the problems raised:
Direct measurement in amperometry was sufficiently sensitive for the analysis of noradrenaline and urinary dopamine, but it was not sufficiently sensitive for the quantitative analysis of urinary adrenaline.
Direct measurement in amperometry was not sufficiently sensitive for the analysis of plasma catecholamines even when starting from a high plasma volume (at least 2 ml).
Direct measurement in amperometry had taken the role of reference technique for a long time, but the amperometric detector proved to be difficult to handle for routine analysis.
Despite the replacement of the amperometer detector with the, more sensitive Coulometric detector, it was still difficult to handle for routine analysis as well as being particularly costly.
After collecting this information relative to the problems arising from the use of the amperometer and coulometric detector they decided to “create”