What you’ re going to read is a quick presentation of Eureka Lab Division and what it did to succeed in researching, developing and producing<\/span><\/span><\/p>\n Many years ago, Dr. Gilberto Coppa , Dr. Stefano Sartori and dr. Angela Cusenza decided to pursue a professional path that few companies had dealt with:<\/span><\/p>\n the analytical procedures existing in clinical laboratories, thanks to the realization of<\/span><\/p>\n using HPLC, GC, GC-MS, LC-MS\/MS chromatographic techniques.<\/span><\/p>\n From the very outset, they concentrated their activity\u00a0on the development of an Analytical Method for the Determination of Urinary and Plasma Catecholamines in HPLC with Fluorimetric Detection.<\/strong><\/span> pheochromocytoma<\/span> paraganglioma<\/strong><\/p>\n<\/div><\/li> neuroblastoma<\/strong><\/p>\n<\/div><\/li><\/ul> The concentration of catecholamines (Noradrenaline, Adrenaline, Dopamine), which are a group of hormones produced by the adrenal glands, are greatly increased in biological fluids in the presence of such pathologies.<\/span><\/p>\n To\u00a0help doctors to properly diagnose these tumor forms, they asked some laboratories about their problems and issues in their structures since the 1970s.<\/span><\/p>\n Here are some of the problems raised:<\/span><\/p>\n After collecting these information relative to the problems arising from the use of the amperometer and coulometric detectors they decided to “create”<\/span><\/p>\n Our\u00a0team worked long for the development of a fluorimetric, chromatographic, analytical method for the determination of catecholamines with the benefit that:<\/span><\/p>\n Their work involved the development of a biologic matrix purification method that was more\u00a0self-explanatory<\/strong> than the methods used up to that time.<\/span><\/p>\n After purification, the sample undergoes a process of derivatization.<\/span><\/p>\n At this point, the derivatized sample is read in fluorimetry, allowing it to obtain excellent sensitivity and specificity<\/strong> for the analysis.<\/span><\/p>\n This has allowed us to reach the much anticipated goal<\/span>:<\/p>\n the analytical procedures existing in clinical laboratories, regarding the dosage of both urine and plasma catecholamines.<\/span><\/p>\n But this was just the beginning …\u00a0Since 2000 the Eureka Lab Division Team, has continued\u00a0 to\u00a0develop\u00a0<\/span><\/p>\n<\/div> Initially the Team dealt with<\/span> We then dedicated\u00a0ourselves to\u00a0<\/span><\/span> Finally, since 2008,\u00a0we have focused\u00a0our work on<\/span> In order to be able to continuously increase the range of new Eureka Kits, the company has for several years been working with the<\/span><\/span><\/p>\n They are Specialists in Clinical Biochemistry, Pharmaco – Toxicology and expert in<\/span> They collect the requests of Doctors who are in close contact with patients and\u00a0iniziate for the development of Chromatographic Analytical Methods that will then be engineered into EUREKA KITS.<\/span><\/span><\/p>\n It’s like having many research and development teams across Italy working to increase the\u00a0development of new chromatographic analytical methods that will then be engineered in the form of ready-to-use kits.<\/span><\/p>\n<\/blockquote>\n After a long research and development work by the Eureka Lab Division Team and by the Study Group of External Authors, Eureka Kit are Validated to GUARANTEE their<\/span><\/p>\n This work is done by the<\/span><\/span><\/p>\n They are also passionate about chromatographic analytical techniques and make available their analytical systems and their human biological samples.<\/span><\/p>\n It is crucial to have the opportunity to use more chromatographic analytical systems<\/strong> and human biological samples<\/strong> , because ONLY THEN\u00a0is it possible to determine<\/span><\/p>\n THE KIT’S STRENGTH<\/strong><\/span> That is why thanks to the work of Eureka Team, together with the group of \u201cAuthors and Validators\u201d , we can<\/p>\n to Clinical Laboratories around the World<\/span> WORK CORRECTLY AND PROVIDE APPROPRIATE RESULTS<\/strong><\/span><\/p>\n To confirm the correct operation and the appropriate results of the Eureka Kits, we have been participating in Quality Control Programs (VEQs) for several years,the World ‘s Largest Range of Diagnostic Kits for chromatographic analytical instruments<\/span><\/h2>\n
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<\/p>\nSimplify, Improve, Standardize<\/span><\/h3>\n
Ready to use Kits<\/span><\/h3>\n
\n The decision to work with Catecholamines was due to the shared thought, along with many Oncologists, that the need of Formulating a Correct Diagnosis of cancer patients was fundamental and extremely important<\/span><\/span><\/p>\n<\/div>
\n<\/span><\/strong><\/p>\n<\/div><\/li>\n
Eureka Lab Division Research and Development Team<\/span><\/h3>\n
\n
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<\/p>\nSimplify, Improve, Standardize<\/span>
\n<\/strong><\/h3>\n![\"\"](\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/chi-produce-eureka-kit-1024x679.jpg\")
<\/p>\nNew Chromatografic Analitycal Methods<\/span><\/h2>\n<\/div>
\n<\/span>Liquid Chromatography (HPLC \/ UHPLC<\/strong>)<\/strong> <\/span><\/span>coupled to<\/span>
\n detectors:<\/span>
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\u00a0 UV\/VIS<\/span><\/p>\n\u00a0 <\/span>FLUORIMETER<\/span>
\n(for analysis of SPECIAL CLINICAL CHEMISTRY, CLINICAL PHARMACOLOGY and OCCUPATIONAL TOXICOLOGY)<\/span><\/p>\n
\n Gas Chromatography (GC)<\/strong><\/span><\/span> coupled to detectors:<\/span><\/span>
\n FID (flame ionization detector)<\/span><\/span><\/p>\n\u00a0ECD (electron capture detector)<\/span><\/span><\/p>\n\u00a0MASS SPECTROMETER<\/span>
\n<\/span>(for analysis of SPECIAL CLINICAL CHEMISTRY, OCCUPATIONAL TOXICOLOGY AND FORENSIC TOXICOLOGY)<\/span><\/p>\n
\n Liquid Chromatography (LC)<\/strong><\/span>\u00a0 <\/strong>c<\/span><\/span>oupled with<\/span>
\n Mass Spectrometer \/ Triple Quadruple \/ Ion Trap<\/span>
\n<\/span>(for analysis of SPECIAL CLINICAL CHEMISTRY, CLINICAL PHARMACOLOGY AND FORENSIC TOXICOLOGY)<\/span><\/span><\/p>\n<\/div>\u201cSTUDY GROUP OF EXTERNAL AUTHORS<\/span>\u201d<\/span><\/strong><\/span><\/h3>\n
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<\/p>\n
\n Chromatographic Analytical Techniques.<\/span><\/span><\/p>\n\n
Accuracy<\/span><\/span><\/h3>\n<\/p>\nPrecision<\/span><\/h3>\n
Recovery<\/span><\/h3>\nSelectivity<\/span><\/h3>\nCalibration Curve<\/span><\/h3>\n<\/strong><\/span><\/h3>\nReproducibility<\/span><\/h3>\n
Stability<\/span><\/h3>\n\u201cSTUDY GROUP OF EXTERNAL VALIDATORS<\/strong><\/span>\u201d<\/span><\/h3>\n
\nand\u00a0its
\nEASY\u00a0OF USE<\/strong><\/span><\/span><\/p>\nGUARANTEE<\/span><\/h3>\n
\nthat the Eureka Kits<\/span><\/p>\n
\nSPECIAL CLINICAL CHEMISTRY INSTAD
\nCLINICAL PHARMACOLOGY INSTAD
\nOCCUPATIONAL TOXICOLOGY G-EQUAS
\nFOREST TOXICOLOGY IST. SUP. DI SANITA’<\/em><\/strong><\/span><\/p>\n<\/div><\/div><\/div>
![](\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/09\/Manuscript-en-cover-small.jpg\" "\\"Manuscript-en-cover-small\\"")
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