{"id":10514,"date":"2006-10-12T22:33:10","date_gmt":"2006-10-12T22:33:10","guid":{"rendered":"http:\/\/www.eurekaone.com\/s6-en-articoli\/c42-en-kits-in-hplc\/tossicologia-occupazionale-metaboliti-di-contaminanti-organici-ad-alto-rischio-2\/"},"modified":"2025-04-01T11:03:39","modified_gmt":"2025-04-01T09:03:39","slug":"occupational-toxicology-hplc","status":"publish","type":"post","link":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/","title":{"rendered":"Occupational Toxicology"},"content":{"rendered":"

Occupational Toxicology<\/h2>\n

Occupational toxicology represents a discipline among medical specialties that aims to analyze, diagnose and prevent occupational diseases due to chemical and biological hazards in the work environment. These include pollution, carcinogenesis, biological factors, ergonomics, etc (Ref. Groneberg_2006).<\/span>
\nHere some examples: <\/span>It has been seen that benzene causes bone marrow damage and cancer upon long exposure to high concentration (Ref: IARC:chemical). <\/span>Benzene is metabolized at the hepatic level via CYP P450 leading to the formation of benzene oxide, from which other metabolites are formed. <\/span>Actually, two minor metabolites such as S-phenyl mercapturic acid and trans, trans-Muconic acid will be present in the urine. <\/span>These ones need to be monitored in the working environment since they are considered valid biomarkers of the benzene exposure due to their specificity (Sedha_2017).<\/span><\/p>\n

Eureka offers a solution to this issue by proposing specific kits: the trans, trans-MuconicAcid and S-phenyl mercapturic acid in urine by LC\/MS (new kit).<\/span><\/p>\n

In this section many different kits, which are of a big use in occupational toxicology, are listed.<\/span><\/p>\n

 <\/p>\n\n\n\n
<\/td>\n<\/td>\n\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\"\"<\/td>\nTotal 2,5 Hexanedione in urine by UV – FAST <\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\nFree 2,5 Hexanedione in urine by Fluorimetry – FAST<\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\nAcetone in urine by UV – FAST <\/a><\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nHippuric Acid\/o-m-p-Methylhippuric Acids in urine by UV – FAST<\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\nPhenylglyoxilic Acid\/Mandelic Acid in urine by UV – FAST <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nPhenylglyoxilic\/Mandelic\/Hippuric\/o-m-p-Methylhippuric Acids in urine by UV – FAST <\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\nPhenylglyoxilic\/Mandelic\/Hippuric\/o-m-p-Methylhippuric Acids in urine by UV – FAST <\/strong>(500 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\ntrans,trans-Muconic Acid (ttMA) in urine by UV – FAST <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nS-phenylmercapturic Acid in urine by Fluorimetry – FAST <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nMethyl-Ethyl-Keton in urine (MEK) by UV – FAST <\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\n1-Hydroxypyrene in urine by Fluorimetry – FAST<\/a><\/strong>(100 tests)<\/td>\n<\/tr>\n
\"\"<\/td>\n1-Hydroxypyrene in urine by Fluorimetry – FAST(500 tests)<\/strong><\/a><\/td>\n<\/tr>\n
\"\"<\/td>\n\n\n\n\n\n\n\n
o-Cresol and Phenol in urine by Fluorimetry – FAST <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n
\"\"<\/td>\no-Cresol and Phenol in urine by Fluorimetry – FAST <\/strong>(500 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nMethanol in urine by UV – FAST <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n
\"\"<\/td>\nFree Eritrocitary Protoporphyrin IX and ZnPP in whole blood by Fluorimetry – FAST<\/a><\/strong> (100 tests)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n
\"Torna<\/td>\n<\/td>\nback to previous page<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Occupational Toxicology Occupational toxicology represents a discipline among […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,3],"tags":[],"class_list":["post-10514","post","type-post","status-publish","format-standard","hentry","category-non-categorizzato","category-uncategorized"],"yoast_head":"\nOccupational Toxicology - Eureka Kit<\/title>\n<meta name=\"description\" content=\"Occupational toxicology represents a discipline among medical specialties\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Occupational Toxicology - Eureka Kit\" \/>\n<meta property=\"og:description\" content=\"Occupational toxicology represents a discipline among medical specialties\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/\" \/>\n<meta property=\"og:site_name\" content=\"Eureka Kit\" \/>\n<meta property=\"article:published_time\" content=\"2006-10-12T22:33:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-01T09:03:39+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"652\" \/>\n\t<meta property=\"og:image:height\" content=\"435\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ANg1a_cUnza\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ANg1a_cUnza\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/\",\"url\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/\",\"name\":\"Occupational Toxicology - Eureka Kit\",\"isPartOf\":{\"@id\":\"https:\/\/www.eurekakit.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg\",\"datePublished\":\"2006-10-12T22:33:10+00:00\",\"dateModified\":\"2025-04-01T09:03:39+00:00\",\"author\":{\"@id\":\"https:\/\/www.eurekakit.com\/#\/schema\/person\/add3353ed09549865e7afe5ae38368ec\"},\"description\":\"Occupational toxicology represents a discipline among medical specialties\",\"breadcrumb\":{\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage\",\"url\":\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg\",\"contentUrl\":\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.eurekakit.com\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Occupational Toxicology\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.eurekakit.com\/#website\",\"url\":\"https:\/\/www.eurekakit.com\/\",\"name\":\"Eureka Kit\",\"description\":\"Eurekakit la pi\u00f9 Ampia Gamma al Mondo di Kit Diagnostici per Strumenti Analitici Cromatografici HPLC, GC, GC-MS e LC-MS\/MS,\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.eurekakit.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.eurekakit.com\/#\/schema\/person\/add3353ed09549865e7afe5ae38368ec\",\"name\":\"ANg1a_cUnza\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.eurekakit.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/1f76f07af7ba5f52944f97ed8a7ffa64?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/1f76f07af7ba5f52944f97ed8a7ffa64?s=96&d=mm&r=g\",\"caption\":\"ANg1a_cUnza\"},\"url\":\"https:\/\/www.eurekakit.com\/en\/author\/ang1a_cunza\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Occupational Toxicology - Eureka Kit","description":"Occupational toxicology represents a discipline among medical specialties","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/","og_locale":"en_US","og_type":"article","og_title":"Occupational Toxicology - Eureka Kit","og_description":"Occupational toxicology represents a discipline among medical specialties","og_url":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/","og_site_name":"Eureka Kit","article_published_time":"2006-10-12T22:33:10+00:00","article_modified_time":"2025-04-01T09:03:39+00:00","og_image":[{"width":652,"height":435,"url":"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg","type":"image\/jpeg"}],"author":"ANg1a_cUnza","twitter_card":"summary_large_image","twitter_misc":{"Written by":"ANg1a_cUnza","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/","url":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/","name":"Occupational Toxicology - Eureka Kit","isPartOf":{"@id":"https:\/\/www.eurekakit.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage"},"image":{"@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage"},"thumbnailUrl":"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg","datePublished":"2006-10-12T22:33:10+00:00","dateModified":"2025-04-01T09:03:39+00:00","author":{"@id":"https:\/\/www.eurekakit.com\/#\/schema\/person\/add3353ed09549865e7afe5ae38368ec"},"description":"Occupational toxicology represents a discipline among medical specialties","breadcrumb":{"@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#primaryimage","url":"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg","contentUrl":"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Occupazionale.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.eurekakit.com\/en\/occupational-toxicology-hplc\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.eurekakit.com\/en\/"},{"@type":"ListItem","position":2,"name":"Occupational Toxicology"}]},{"@type":"WebSite","@id":"https:\/\/www.eurekakit.com\/#website","url":"https:\/\/www.eurekakit.com\/","name":"Eureka Kit","description":"Eurekakit la pi\u00f9 Ampia Gamma al Mondo di Kit Diagnostici per Strumenti Analitici Cromatografici HPLC, GC, GC-MS e LC-MS\/MS,","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.eurekakit.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.eurekakit.com\/#\/schema\/person\/add3353ed09549865e7afe5ae38368ec","name":"ANg1a_cUnza","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.eurekakit.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/1f76f07af7ba5f52944f97ed8a7ffa64?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/1f76f07af7ba5f52944f97ed8a7ffa64?s=96&d=mm&r=g","caption":"ANg1a_cUnza"},"url":"https:\/\/www.eurekakit.com\/en\/author\/ang1a_cunza\/"}]}},"_links":{"self":[{"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/posts\/10514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/comments?post=10514"}],"version-history":[{"count":35,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/posts\/10514\/revisions"}],"predecessor-version":[{"id":25020,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/posts\/10514\/revisions\/25020"}],"wp:attachment":[{"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/media?parent=10514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/categories?post=10514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.eurekakit.com\/en\/wp-json\/wp\/v2\/tags?post=10514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}