{"id":10516,"date":"2006-10-12T22:33:10","date_gmt":"2006-10-12T22:33:10","guid":{"rendered":"http:\/\/www.eurekaone.com\/s6-en-articoli\/c42-en-kits-in-hplc\/monitoraggiocontrollo-dellabuso-acuto-e-cronico-di-alcool-etilico-2\/"},"modified":"2025-04-01T11:23:15","modified_gmt":"2025-04-01T09:23:15","slug":"monitoring-control-of-acute-and-chronic-abuse-of-ethyl-alcohol-hplc","status":"publish","type":"post","link":"https:\/\/www.eurekakit.com\/en\/monitoring-control-of-acute-and-chronic-abuse-of-ethyl-alcohol-hplc\/","title":{"rendered":"Monitoring\/Control of acute and chronic abuse of Ethyl Alcohol"},"content":{"rendered":"<h2>Forensic Toxicology<\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">The term \u201cToxicology\u201d, also known as the \u201cScience of Safety\u201d, refers to the scientific field that investigates the damaging effects that chemicals, drugs, others substances or various settings can have on the environment, individuals and animals (Ref. https:\/\/www. <\/span><span style=\"color: #000000;\">niehs.nih.gov). <\/span><span style=\"color: #000000;\">Among the several branches that Toxicology is divided into, here we focus on Forensic Toxicology. <\/span><span style=\"color: #000000;\">Forensic toxicology analyzes toxic substances and their adverse effects in human or animals with medical-legal implications (https:\/\/sciencemonk.com\/forensic-toxicology\/). The toxicological analyses in the forensic field involve the examination of the so-called \u201cconventional\u201d matrices (whole blood, urine) and \u201calternatives\u201d such as the hair oral fluid and sweat. <\/span><span style=\"color: #000000;\">Their respective outcome, alone or in combination, provide useful elements for a correct diagnosis with forensic\/medico-legal meaning in various fields.\u00a0 <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Several matrices can be used depending on the case of study:<\/span><br \/>\n<span style=\"color: #000000;\">\u2022 Urine is the election matrix for determining the \u201crecent\u201d consumption of substances of abuse. <\/span><br \/>\n<span style=\"color: #000000;\">\u2022 Hair matrix can be investigated to verify the status of a chronic user, as well as previous behaviors of use\/abuse. The segmental analysis of hair helps to reconstruct the chronology of the consumption fairly accurately. Considering the overall hair replacement time in a sufficiently extended body area, a \u201ctime window\u201d of about 9-18 months can be evaluated in relation to the type of hair and its natural growth.<\/span><br \/>\n<span style=\"color: #000000;\">\u2022 Whole blood matrix has been regulated and it is the election matrix to investigate the \u201ccurrent\u201d use of substances of abuse. However, it is an invasive procedure and it can lead to risks for both the patient and the operator.<\/span><br \/>\n<span style=\"color: #000000;\">\u2022 Saliva matrix (more properly oral fluid) represents an alternative to whole blood, but not yet regulated. As well as whole blood matrix, it can be used to check the \u201ccurrent\u201d use of substances of abuse. Moreover, it has the advantage to be a non-invasive collection method.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<table border=\"0\">\n<tbody style=\"text-align: left;\">\n<tr style=\"text-align: left;\">\n<td style=\"text-align: left;\" align=\"center\" valign=\"top\"><\/td>\n<td style=\"text-align: left;\"><\/td>\n<td valign=\"top\">\n<table border=\"0\">\n<tbody>\n<tr style=\"height: 48px;\">\n<td style=\"height: 48px;\"><\/td>\n<td style=\"height: 48px;\"><img decoding=\"async\" class=\"wp-image-11700 alignleft\" src=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense.jpg\" alt=\"\" width=\"252\" height=\"168\" srcset=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense-200x133.jpg 200w, https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense-300x200.jpg 300w, https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense-400x267.jpg 400w, https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense-600x400.jpg 600w, https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/06\/HPLC-Tossicologia-Forense.jpg 663w\" sizes=\"(max-width: 252px) 100vw, 252px\" \/><\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td style=\"text-align: center;\"><strong>CHRONIC ALCOHOL ABUSE<br \/>\n<\/strong><\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td style=\"text-align: center;\"><strong>\u00a0<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 19px;\">\n<td style=\"height: 19px;\"><img decoding=\"async\" class=\"alignleft size-full wp-image-11945\" src=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/09\/blue-bullet-25x21px.png\" alt=\"\" width=\"25\" height=\"19\" \/><\/td>\n<td style=\"height: 19px;\"><a href=\"https:\/\/www.eurekakit.com\/en\/cdt-test-carbohydrate-deficient-transferrin-sierico-in-uvvis-fast-2\/\"><strong>CDT(Carbohydrate-Deficient Transferrin) Test in serum by UV\/VIS &#8211; FAST MONOREAGENT <\/strong>(100 tests)<\/a><\/td>\n<\/tr>\n<tr style=\"height: 26px;\">\n<td style=\"height: 26px;\"><img decoding=\"async\" class=\"alignleft size-full wp-image-11945\" src=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/09\/blue-bullet-25x21px.png\" alt=\"\" width=\"25\" height=\"19\" \/><\/td>\n<td style=\"height: 26px;\"><a href=\"https:\/\/www.eurekakit.com\/en\/cdtcarbohydrate-deficient-transferrin-test-in-serum-by-uvvis-fast-monoreagent\/\"><strong>CDT(Carbohydrate-Deficient Transferrin) Test in serum by UV\/VIS &#8211; FAST MONOREAGENT <\/strong><\/a>(<a href=\"https:\/\/www.eurekakit.com\/en\/cdtcarbohydrate-deficient-transferrin-test-in-serum-by-uvvis-fast-monoreagent\/\">500 tests) <\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table style=\"height: 132px;\" border=\"0\">\n<tbody style=\"text-align: left;\">\n<tr style=\"text-align: left;\">\n<td style=\"text-align: left;\"><a href=\"https:\/\/www.eurekakit.com\/en\/lc-hplc-kits\/\"><img decoding=\"async\" class=\" size-full wp-image-92\" title=\"Torna alla pagina precedente\" src=\"http:\/\/www.eurekakit.com\/wp-content\/uploads\/2006\/10\/back.png\" alt=\"Torna alla pagina precedente\" width=\"32\" height=\"32\" \/><\/a><\/td>\n<td style=\"text-align: left;\"><\/td>\n<td style=\"text-align: left;\"><a href=\"https:\/\/www.eurekakit.com\/en\/lc-hplc-kits\/\">back to previous page<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Forensic Toxicology The term \u201cToxicology\u201d, also known as [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,3],"tags":[],"class_list":["post-10516","post","type-post","status-publish","format-standard","hentry","category-non-categorizzato","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - 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