{"id":11082,"date":"2019-08-09T15:50:35","date_gmt":"2019-08-09T13:50:35","guid":{"rendered":"https:\/\/www.eurekakit.com\/en\/?p=11082"},"modified":"2025-06-18T11:35:16","modified_gmt":"2025-06-18T09:35:16","slug":"free-vma-5-hiaa-hva-in-urine-by-fluorimetry-hplc","status":"publish","type":"post","link":"https:\/\/www.eurekakit.com\/en\/free-vma-5-hiaa-hva-in-urine-by-fluorimetry-hplc\/","title":{"rendered":"Free VMA\/5-HIAA\/HVA in urine by Fluorimetry &#8211; FAST"},"content":{"rendered":"<table style=\"width: 100%;\" border=\"0\">\n<tbody style=\"text-align: left;\">\n<tr style=\"text-align: left;\">\n<td style=\"text-align: center; width: 19.0262%;\" valign=\"top\"><img decoding=\"async\" class=\"alignleft wp-image-12305\" src=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2019\/07\/prodotti-1.gif\" alt=\"\" width=\"240\" height=\"147\" \/><\/td>\n<td style=\"text-align: left; width: 0.85034%;\"><\/td>\n<td style=\"text-align: left; width: 84.8921%;\" valign=\"top\">\n<p style=\"text-align: justify;\"><strong>Free VMA\/5-HIAA\/HVA in urine by Fluorimetry &#8211; FAST<\/strong> (<strong><span style=\"color: #0000ff;\">code<\/span><\/strong>\u00a0 <strong><span style=\"color: #0000ff;\">Z14610<\/span><\/strong>) &#8211; 100 tests package<\/p>\n<p style=\"text-align: justify;\"><strong>INSIGHTS<\/strong><\/p>\n<p style=\"text-align: justify;\">The catabolic process of monoamines is in part neuronal and happens in the mitochondria and it is catalyzed by the Monoamine oxidase (MAO) and, partly extra neuronal for catecholamines, it is catalyzed by COMT.\u00a0 In particular, we obtain dihydroxyphenylacetic acid from dopamine by the action of the MAO, which is transformed by COMT into Homovanillic Acid (HVA). 3,4-Dihydroxypropanoic originates from Noradrenaline and Adrenaline and by interacting with COMT we have the synthesis of Vanilmandelic acid (VMA). Values of these analytes out of the norm indicate the presence of Pheochromocytoma, paraganglioma or neuroblastoma. 5-hydroxyindolacetic acid (5-HIIA) is the principal final product of serotonin metabolism. The determination of its concentration in urine is utilized for the diagnosis of a neuroendocrine tumor.<\/p>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"326\"><strong><span style=\"text-decoration: underline;\">Principle of the Method<\/span><\/strong><strong> :<\/strong><strong>\u00a0<\/strong><\/td>\n<td valign=\"top\" width=\"326\"><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" valign=\"top\" width=\"652\">Vanillymandelic Acid, 5-Hydroxyindoleacetic Acid and Homovanillic Acid are diluted with a suitable diluent and directly injected into the HPLC System.<\/p>\n<table style=\"width: 68.23%;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 15.2228%; height: 32px; text-align: center;\" valign=\"middle\"><a href=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2024\/09\/Z14610-VMA-HVA-5-HIAA-Fast-Rev.11-EN.pdf\"><img decoding=\"async\" class=\" size-full wp-image-124\" style=\"vertical-align: bottom;\" src=\"http:\/\/www.eurekakit.com\/wp-content\/uploads\/2010\/02\/right_blue_arrow.gif\" alt=\"right_blue_arrow\" width=\"32\" height=\"32\" \/><\/a><\/td>\n<td style=\"width: 287.541%;\" valign=\"middle\"><a href=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2024\/09\/Z14610-VMA-HVA-5-HIAA-Fast-Rev.11-EN.pdf\"><strong><span style=\"color: #0000ff;\">IFU\u00a0<\/span><\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.2228%; height: 32px; text-align: center;\" valign=\"middle\"><a href=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2024\/09\/Z14610-VMA-HVA-5-HIAA-Fast-Rev.11-EN.pdf\"><img decoding=\"async\" class=\" size-full wp-image-124\" style=\"vertical-align: bottom;\" src=\"http:\/\/www.eurekakit.com\/wp-content\/uploads\/2010\/02\/right_blue_arrow.gif\" alt=\"right_blue_arrow\" width=\"32\" height=\"32\" \/><\/a><\/td>\n<td style=\"width: 287.541%;\" valign=\"middle\"><a href=\"https:\/\/www.eurekakit.com\/wp-content\/uploads\/2025\/05\/Z14611-VMA-HVA-5-HIAA-mobile-Phase-rev-1-EN.pdf\"><span style=\"color: #0000ff;\"><strong>IFU MOBILE PHASE\u00a0<\/strong><\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"height: 59px;\" border=\"0\">\n<tbody>\n<tr>\n<td><a title=\"Torna alla pagina precedente\" href=\"http:\/\/www.eurekakit.com\/en\/en-articoli\/en-kits-in-hplc\/chimico-clinica-speciale-2\/\"><img decoding=\"async\" class=\" size-full wp-image-92\" title=\"Torna alla pagina precedente\" src=\"http:\/\/www.eurekakit.com\/wp-content\/uploads\/2006\/10\/back.png\" alt=\"Torna alla pagina precedente\" width=\"32\" height=\"32\" \/> <\/a><\/td>\n<td><\/td>\n<td><a href=\"https:\/\/www.eurekakit.com\/en\/special-clinical-chemistry-hplc-2\/\">Back to previous page<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Free VMA\/5-HIAA\/HVA in urine by Fluorimetry &#8211; FAST (code\u00a0 Z14610) &#8211; 100 tests package INSIGHTS The catabolic process of monoamines is in part neuronal and happens [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[425,1],"tags":[],"class_list":["post-11082","post","type-post","status-publish","format-standard","hentry","category-en-articoli","category-non-categorizzato"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Free VMA\/5-HIAA\/HVA in urine by Fluorimetry - FAST - Eureka Kit<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.eurekakit.com\/en\/free-vma-5-hiaa-hva-in-urine-by-fluorimetry-hplc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Free VMA\/5-HIAA\/HVA in urine by Fluorimetry - FAST - Eureka Kit\" \/>\n<meta property=\"og:description\" content=\"Free VMA\/5-HIAA\/HVA in urine by Fluorimetry &#8211; 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