{"id":12330,"date":"2019-09-09T17:39:53","date_gmt":"2019-09-09T15:39:53","guid":{"rendered":"https:\/\/www.eurekakit.com\/en\/?p=12330"},"modified":"2025-06-16T10:06:17","modified_gmt":"2025-06-16T08:06:17","slug":"irinotecan-plasma-by-lc-ms","status":"publish","type":"post","link":"https:\/\/www.eurekakit.com\/en\/irinotecan-plasma-by-lc-ms\/","title":{"rendered":"Irinotecan in plasma by LC\/MS –"},"content":{"rendered":"\n\n\n
\"Prodotti\"<\/td>\n<\/td>\n\n

Irinotecan\u00a0 in plasma by LC\/MS (code\u00a0 LC94010<\/span><\/strong>)\u00a0 100 test package.<\/p>\n

INSIGHTS<\/strong>
\nIrinotecan is an antineoplastic chemotherapy drug of the class of camptothecins (drugs extracted from the bark of Camptotheca acuminata). Actually, Irinotecan is a pro drug. Its activation occurs at a hepatic level thanks to the transformation effected by the enzymecarboxesterase in SN 38. Irinotecan and SN 38 are then eliminated mainly through the bile. Therefore, the dosage should be reduced in patients with hepatic insufficiency.<\/p>\n

Principle of the\u00a0 Method:<\/span><\/strong><\/p>\n

\u00a0Irinotecan and its primary active metabolite are analyzed by treating the plasma with a suitable deproteinization reagent. The solution is directly injected into the LC \/ MS.<\/p>\n\n\n\n\n\n
\"right_blue_arrow\"<\/a><\/td>\nIFU<\/span><\/strong><\/a><\/td>\n<\/tr>\n
\"right_blue_arrow\"<\/a><\/td>\nIFU MOBILE\u00a0<\/span><\/strong>PHASE M1<\/span><\/strong><\/a><\/td>\n<\/tr>\n
\"right_blue_arrow\"<\/a><\/td>\nIFU MOBILE\u00a0<\/span><\/strong>PHASE M2<\/span><\/strong><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\"Torna<\/a><\/td>\n<\/td>\nback to previous page<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Irinotecan\u00a0 in plasma by LC\/MS (code\u00a0 LC94010)\u00a0 100 test package. INSIGHTS Irinotecan is an antineoplastic chemotherapy drug of the class of camptothecins (drugs extracted from the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-12330","post","type-post","status-publish","format-standard","hentry","category-non-categorizzato"],"yoast_head":"\nIrinotecan in plasma by LC\/MS - Eureka Kit<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.eurekakit.com\/en\/irinotecan-plasma-by-lc-ms\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Irinotecan in plasma by LC\/MS - Eureka Kit\" \/>\n<meta property=\"og:description\" content=\"Irinotecan\u00a0 in plasma by LC\/MS (code\u00a0 LC94010)\u00a0 100 test package. 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