3-Methylindole (Skatole) in urine by Fluorimetry – FAST

3-Methylindole (Skatole) in urine by Fluorimetry – FAST (code  Z60010) – 100 tests package.

INSIGHTS
3-methyl indole or skatole is present in faeces and is derived from biotransformation (decarboxylation) of theamino acid Tryptophan that is found in the digestive tract of mammals. In the colon, there is a large bacterial flora that may be subject to changes that make it harmful to health.When this flora is balanced and useful to the body, there is a balance that is called “eubiosis”.When, however, unwanted bacteria appear, they alter the balance and create the “intestinal disbiosis”, unfortunately a very common condition. If the intestinal flora is not balanced, the amino acids derived from undigested proteins undergo a decarboxylation process that produces toxic amines, such as 3-methyl indole, resulting from tryptophan. Many of these amines are powerful vasoconstrictive poisons. It should also be noted that 3-methyl indole is responsible for the particularly odour of faeces.

Principle of the Method:

 The 3-Methylindole is analyzed by treating the urine with a suitable diluent and the resulting solution is directly injected into HPLC.

	IFU
	IFU MOBILE PHASE