Free Catecholamines in urine by Fluorimetry – FAST (Extractive Method)

Free Catecholamines in urine by Fluorimetry – FAST (code  Z10610) – 100 tests package.

INSIGHTS
Catecholamines are used as markers when there is the suspicion of a pheochromocytoma or paraganglioma or neuroblastoma. They can also be requested when the pheochromocytoma has already been surgically removed and you want to monitor the fallout. The blood test is more useful when the patient is affected by persistent hypertension or such episodes; this is because the hormones do not remain in the circulatory system long enough, but they are utilized, metabolized and expelled. The exam on the urinary matrix measures the quantity of catecholamines released in 24 hours. Since the hormonal concentrations vary over the day, the examination of the urine sample can determine an excessive production that would be overlooked on a plasmatic matrix.

Principle of the Method:

Catecholamines (Dopamine, Epinephrine and  Norepinephrine,) after purification with Clean up columns, are derivatized with 2 specific reagents and incubate at 70 °C for 15 minutes. The derivatized solution, is injected in HPLC.

	IFU
	IFU MOBILE PHASE