Drugs of Abuse in hair by GC/MS

Drugs of Abuse in hair by GC/MS
(Morphine, Codeine, Dihydrocodeine, 6-MAM, Ethylmorphine, Cocaine, Benzoilecgonine, Cocaethylene, Methadone, EDDP, Buprenorphine, Norbuprenorphine, Amphetamine, Methamphetamine, 3,4-MDA, 3,4-MDE, 3,4-MDMA, MBDB) (code  GC49010) – 50 tests package.

INSIGHTS

Once embedded in the hair, by the systemic circulation and by the contribution of sweat and sebum, substances of abuse remain impounded in the keratinous array in a stable way over time as a function of their lipophilic, molecular weight, the pKa and the steric encumbrance. The analysis of substances of abuse in keratinous array is an ideal addendum to the analysis of blood or urine as it provides information regarding an earlier time than that covered by other biological matrices and refers to a longer time period (one or more months) as a function of the length of the hair. The search for substances of abuse in hair can be used to test use, abuse and misuse over time to determine intensity and its history and then provide analytical data with medico-legal value. Determination in hair may be required in the following cases: deaths related to the use of substances of abuse, assessment of ineligibility for driving, criminal liability, reliance custody of infants, prenatal exposure to substances of abuse and finally as confirmation of sporadic  consumption or a dependency in workers

Principle of the Method:

This method determines Morphine, Codeine, Dihydrocodeine, 6-Monoacetylmorphine, Ethylmorphine, Cocaine, Beg, Cocaethylene, Methadone, Amphetamine, Methamphetamine, MDMA, MDA , MDE, MBDB, Buprenorphine, EDDP after hydrolysis of the keratin matrix, SPE extraction and reading by GC-MS.

	IFU