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Antidepressants in serum and in plasma by LC-MS – (code LC84010) 100 test package.
INSIGHTS
Antidepressants are a class of medications used in emotional and mood disorders, which can evolve into psychosis and other symptoms such as anhedonia, self-devaluation, indecision, lack of appetite, hyperphagia, insomnia, hypersomnia, recurring thoughts of suicide or murderand somatization of pain. These drugs are divided into various classes according to their mechanism of action: – monoamine oxidase inhibitors, tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, noradrenaline reuptake inhibitors, dopamine and noradrenaline reuptake inhibitors, dopamine reuptake inhibitors, serotonergic drugs, specific noradrenergic and serotonergic antidepressants, melatonergic drugs. Given the large number of antidepressants on the market and their increasing use, there is a need for physicians to monitor their plasma concentration in order to avoid episodes of overdose
Principle of the Method:
This method allows the determination of a number of antidepressant drugs and their main active metabolites: Amitriptyline, Citalopram and Escitalopram, Clomipramine, Desipramine, Desvenlafaxine, Doxepine, Duloxetine, Fluoxetine,Fluvoxamine, Imipramine, Norclomipramine, Nordoxepine, Norfluoxetine, Nortriptyline, Paroxetine, Sertraline, Venlafaxine
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