o-Cresol and Phenol in urine by Fluorimetry – FAST  (code  Z55310) – 100 tests package.

INSIGHTS
Phenol is used in numerous organic synthesis and disinfectants. It is toxic by itself if absorbed through the skin, respiratory system or, accidentally, through the digestive system. In the organism, Phenol, is partially conjugated with Sulfuric Acid and Glucuronic Acid. Phenol is irritant to mucous, eyes and skin. O-Cresol is a urinary metabolite of Toluene, a substance used in the production of commonly used materials (glues, paints,
lacquers, ink etc.) and it is present also as a micro pollutant in the environment. Thus all the population is exposed to modest concentrations of Toluene. 20% of the absorbed amount is expelled unmodified by the respiratory system and the remainder is biologically transformed. The main metabolites are Hippuric Acid, O-Cresol and Benzoic Acid.

Principle of the Method:

o-Cresol and Phenol, o-Cresol and Phenol, after hydrolysis at 95 ° C for 30 minutes, are first buffered and then diluted with appropriate solvents; the solution is directly injected into HPLC.

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right_blue_arrow IFU MOBILE PHASE 

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