Ethylglucuronide and Ethylsulfate in urine by LC/MS

Ethylglucuronide and Ethylsulfate in urine by LC/MS (code  LC78010) – 100 tests package.

INSIGHTS
Ethyl glucuronide is a non-volatile molecule, polar, relatively stable and formed by conjugation of Ethanol with Glucuronic Acid with mediation of UDP-glucuronyl-transferase (UGT), a superfamily of highly polymorphic enzymes. The Ethylglucuronide seems to be synthesized by various isoforms with UGT function. The lack of one of these isoforms in an individual, does not indicate significant variations in the formation of Ethyl glucuronide. Therefore, individuals belonging to different ethnic groups, most likely synthetize the same percentage of the compound after Alcohol consumption. It has been estimated that only 0.02-0.06 % of Ethanol consumed is transformed into Ethyl glucuronide.

Principle of the  Method:

This method allows the determination of urinary Ethylglucuronide and Ethylsulfate after a simple dilution of the sample and reading by LC-MS.

	IFU
	IFU MOBILE PHASE M1
	IFU MOBILE PHASE M2