Sotalol in plasma by Fluorimetry – FAST (code Z78110) – 100 tests package.

 

INSIGHTS

Sotalol is an active ingredient specifically used in the treatment cardiac arrhythmias. Among nonselective betablockers, sotalol is one of the most water-soluble and in addition to beta-blocking activity, is able to block the potassium channel, acting as an antiarrhythmic class III. This allows the use of the drug for atrial fibrillation in conjunction with ventricular tachyarrhythmias. Sotalol is a drug that has long been studied because of its unique pharmacological properties, showing both beta-blocking and blocking activity of the potassium channels

 

Principle of the Method:

 The Sotalol is analysed by treating the plasma with appropriate deproteinization reagent. The solution is centrifuged and, after diluting the supernatant, injected into HPLC.

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