Confirmatory method for drugs of abuse in saliva by LC/MS 

The oral fluid can be used for monitoring drugs of abuse in the workplace,
in Clinical Toxicology, in Criminal Justice and in driving under
the influence of substances.

The main advantages of the oral fluid are:

• easiness and non-invasiveness in the sample collection
• it is not necessary to use special toilet facilities
• the collection of the sample by personnel of the same sex of the patient is not necessary
• it is difficult to adulterate the sample
• the risk of infection for those who collect the sample is certainly lower than blood
• the fluid better reflects the recent use of drugs