Differentiated Porphyrins in urine by Fluorimetry – FAST (code  Z73010) – 100 tests package.

INSIGHTS
Acute porphyries are metabolic diseases that cause alterations in biochemical processes, mostly in the liver. They neither cause hematologic diseases nor hepatic damage. When porphyrins accumulate in the skin, it becomes particularly sensitive to light causing the typical symptoms of porphyria. The accumulation in the liver of simpler chemical precursors is responsible for more acute attacks. Patterns of porphyrin accumulation in erythrocytes and plasma and excretion of heme precursors in urine and faeces allow to detect and differentiate porphyrias.

Principle of the method :

 This method allows to analyze the absolute concentrations of porphyrins, the samples are diluted with a suitable diluent and directly injected into HPLC using a binary gradient pump.

right_blue_arrow IFU
right_blue_arrow IFU MOBILE PHASE M1  
right_blue_arrow IFU MOBILE PHASE M2  

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