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Free Metanephrine in plasma by LC/MS (extractive Method) (code LC97110) 96 test package. The dosage of urinary metanephrines represents a reliable test for the screening of pheochromocytoma. These substances derive from the metabolism of catecholamines, hormones produced and secreted by medullary of the adrenal glands, in order to prepare the organism for stressful events. Pheochromocytoma is a tumor that affects adrenalin glands causing a hypersecretion of catecholamines; as a result, levels of Adrenaline and Noradrenaline increase, as wells as their metabolites, called metanephrines. They form inside the tumor and are secreted inconsistently by the tumor. Principle of the Method: Plasma sample is treated with SPE extraction and injected in LC-MS/MS
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