Hippuric Acid/o-m-p-Methylhippuric Acids in urine by UV – FAST

Hippuric Acid/o-m-p-Methylhippuric Acids in urine by UV – FAST (code  Z06110) – 100 tests package.

INSIGHTS
The determination of Hippuric Acid ( HPA ) in urine is important to evaluate the risk due to exposure to Toluene . Toluene is metabolised mostly in Benzoic Acid and subsequently combined with Glycine is eliminated by urine as Hippuric Acid. The determination of o-m-p Methylhippuric Acid ( m-MHPA, o-MHPA and p-MHPA ) is important to evaluate the risk due to exposure to a mixture of o-m-p-Xilene. Xilene, which is present as a mixture of three isomers o-m-p, is metabolised in o-m-p-Methyl-Benzoic and after conjugation with Glycine is eliminated by urine as a mixture of o-m-p-Methyl-Hippuric Acids.

Principle of the  Method:

Hippuric Acid and o-m-p Methylhippuric Acids are analysed after dilution and after the addition of a stabilization solution. This solution is then directly injected into HPLC System.

	IFU
	IFU MOBILE PHASE