Methyl-Ethyl-Keton in urine (MEK) by UV – FAST

Methyl-Ethyl-Keton in urine (MEK) by UV – FAST  (code  Z24110) – 100 tests package

INSIGHTS
MEK, also known as methyl ethyl ketone or butanone, occurs as a colorless liquid with a sweet smell like acetone. Is is volatile, flammable and potentially explosive. It is mainly used as a solvent, and for this reason it is used in processes involving rubbers, resins, nitrocellulose coatings, cellulose acetate and vinyl films. MEK is absorbed through the skin and through inhalation. It causes irritation to the nose and throat at  concentrations close to 100 ppm, and eyes at 200 ppm. Facial dermatitis is reported at concentrations of between 300 and 600 ppm; at higher concentrations it can cause narcosis. In literature it is also described as a possible cause of optic neuritis due probably to its transformation into methanol. The half life of exhaled MEK is approximately 60 minutes and in blood is about 4 hours. Although it is metabolized in the body, it is also found unchanged in the urine.

Principle of the Method:

M.E.K. is derivatized with a suitable reagent and incubated at 70 °C for 30 minutes. After Clean-up Columns purification, 50μl of solution are injected into the HPLC.

	IFU
	IFU MOBILE PHASE