Phenylglyoxilic/Mandelic/Hippuric/o-m-p-Methylhippuric Acids in urine by UV – FAST

(code  Z06610)- 100 tests package.

____________________________INSIGHTS_______________________________
The determination of urinary Hippuric Acid is used for the biological monitoring of people exposed to Toluene.
Toluene is transformed in the organism mostly to Benzoic Acid, which, after conjugating with Glycine, is
expelled by urine under the form of Hippuric Acid. The determination of o-m-p-Methylhippuric Acids is used
for the biological monitoring of people exposed to o-m-p-Xylene. Xylene is present as a mixture of the three
isomers o-m-p and it is transformed in a mixture of o-m-p-Methyl-Benzoic Acids which after conjugation with
Glycine are expelled as a mixture of o-m-p-Methylhippuric Acids by urine.

Principle of the Method:

Phenylglyoxilic Acid, Mandelic Acid, Hippuric Acid and o-m-p Methylhippuric Acids are analyzed after dilution and after the addition of a stabilization solution. This solution is then directly injected into HPLC System.

right_blue_arrow Methodology

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