VMA, 5-HIAA and HVA IN URINE BY LC/MS

VMA, 5-HIAA and HVA IN URINE BY LC/MS (code  LC14610)  100 test package.

INSIGHTS
The catabolic process of monoamines is in part neuronal and happens in the mitochondria by the Monoamine oxidase (MAO) and, partly extra neuronal for catecholamines, by COMT. In particular: Homovanillic Acid (HVA) is the major metabolite of Dopamine while Vanillymandelic Acid (VMA) is the main metabolite of norepinephrine and epinephrine.
– 5-hydroxyindolacetic acid (5-HIIA) is the principal final product of serotonin metabolism. The determination of its concentration in urine is utilized for the diagnosis of a neuroendocrine tumor

Principle of the  Method:

The sample was diluted and injected into LC-MS/MS

	IFU
	IFU MOBILE PHASE M1
	IFU MOBILE PHASE M2